Key result
Postmenopausal estrogen replacement therapy is linked to ~18% lower common carotid arterial stiffness versus nonusers.
Why the study?
Does postmenopausal estrogen replacement therapy reduce common carotid arterial stiffness in women?
Population
172 women from the Baltimore Longitudinal Study of Aging, mean age 55.6 +/- 16.4 years, including 37 current…
Comparison
Current postmenopausal estrogen replacement… vs Postmenopausal nonusers of estrogen replacement…
Design
Cross-sectional
Authors
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Should not yet change practice; hypothesis-generating for ERT effects on arterial stiffness.
Observational (n=172)
Does postmenopausal estrogen replacement therapy reduce common carotid arterial stiffness in women?
Absolute Event Rate: 8% vs 9.7%
p-value: p=< 0.01
Postmenopausal estrogen replacement therapy is associated with reduced age-related increases in common carotid arterial stiffness.
Yoji Nagai (1999) conducted an observational in Carotid arterial stiffness (n=172). Estrogen replacement therapy (ERT) vs. Postmenopausal nonusers was evaluated on Common carotid arterial (CCA) stiffness index (p=< 0.01). Postmenopausal estrogen replacement therapy was associated with a lower common carotid arterial stiffness index compared to nonusers (8.0 vs 9.7, p<0.01).
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