What question did this study set out to answer?

Investigate whether equine-virulent epizootic Venezuelan encephalitis virus persisted in Central American habitats following the extensive 1969 epidemic.

July 1, 1976American Journal of Epidemiology

Search for Persistent Epizootic Venezuelan Encephalitis Virus in Guatemala, El Salvador and Nicaragua During 1970–197512

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Investigate whether equine-virulent epizootic Venezuelan encephalitis virus persisted in Central American habitats following the extensive 1969 epidemic.
Conducted longitudinal field surveillance between 1970 and 1975 across Guatemala, El Salvador, and Nicaragua using sentinel horses and sentinel hamsters.
Sampled wild terrestrial mammals, vectors, and sentinel animals to evaluate viral isolation, Vero cell plaque characteristics, hemagglutination inhibition, and neutralizing antibody titers.
No epizootic virus transmission was detected in the 1969 epicenter region of Guatemala and El Salvador; sentinel hamsters survived, sentinel horses lacked antibodies, and wild rats and mosquitoes lacked detectable virus.
Isolates and antibodies identified near Guatemalan ranches displayed characteristics and plaque morphologies consistent with enzootic rather than epizootic strains.
The only epizootic activity identified during 1970–1975 occurred in Nicaragua in 1972, resulting in several hundred equine fatalities, with persistence versus reintroduction unresolved.

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Implication

Longitudinal surveillance reveals minimal persistence of epizootic Venezuelan encephalitis virus in Central American equine and vector populations, suggesting epidemic strains rarely establish...

Cite This Study

Scherer et al. (1976) studied this question.

synapsesocial.com/papers/6aa213453d48341d53efa180 https://doi.org/10.1093/oxfordjournals.aje.a112274

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Implication

Longitudinal surveillance reveals minimal persistence of epizootic Venezuelan encephalitis virus in Central American equine and vector populations, suggesting epidemic strains rarely establish...

Search for Persistent Epizootic Venezuelan Encephalitis Virus in Guatemala, El Salvador and Nicaragua During 1970–197512

Key Points

Discussion

Implication

Cite This Study

Search for Persistent Epizootic Venezuelan Encephalitis Virus in Guatemala, El Salvador and Nicaragua During 1970–197512

Key Points

Discussion

Implication

Cite This Study

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