Key result
Emergency AVR and CABG succeeds in a patient with osteogenesis imperfecta and coronary artery dissection.
Case Report (n=1)
Demonstrates successful emergency surgical management of iatrogenic coronary dissection in a high-risk patient with osteogenesis imperfecta.
May inform emergency combined AVR+CABG for iatrogenic dissection in osteogenesis imperfecta; leaves open optimal strategies in this rare, fragile population.
Osteogenesis imperfecta is an inherited connective tissue disorder. Aortic root dilation, aortic insufficiency and mitral valve prolapse are uncommon cardiovascular manifestations of osteogenesis imperfecta. Cardiac surgery in patients with osteogenesis imperfecta involves a high risk of complication rate. We report a case of coronary artery dissection induced by coronary angiogram in a patient with osteogenesis imperfecta and severe aortic regurgitation. In this case, the dissection of a coronary artery was not completely sealed by coronary stenting, and followed by successful combined aortic valve replacement and coronary artery bypass grafting on an emergency basis.
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Markku Eskola (2002) conducted a case report in Osteogenesis imperfecta and severe aortic regurgitation (n=1). Combined aortic valve replacement and coronary artery bypass grafting was evaluated. Combined aortic valve replacement and coronary artery bypass grafting was successfully performed on an emergency basis in a patient with osteogenesis imperfecta and coronary artery dissection.
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