Key result
Urinalysis screening reveals proteinuria in ~19% of apparently healthy adults.
Why the study?
What is the prevalence of urinary abnormalities among apparently healthy adults in an urban Nigerian population?
Cross-Sectional (n=1,048)
No
What is the prevalence of urinary abnormalities among apparently healthy adults in an urban Nigerian population?
Urinary abnormalities, particularly proteinuria, are highly prevalent among apparently healthy adults in urban Nigeria, highlighting the potential utility of routine dipstick screening.
Supports targeted screening research in urban African adults; leaves open whether routine dipstick testing improves outcomes.
Background: Urinalysis is a simple and cheap method of screening for systemic diseases including kidney disease and may open a window of opportunity for prevention/early treatments especially in resource-constrained settings like Nigeria. We therefore studied the pattern of urinary abnormalities among an apparently healthy urban population. Methods: Mid-stream clean catch urine samples were collected from 1048 apparently healthy subjects and tested for urinary abnormalities using the dipstick method following a health promotional talk in Idi-araba, a Lagos slum. Results: A total of 1048 randomly selected subjects with a mean age of 38.7 14.5 years (age range 18-85 years) were screened. This consisted of 597 (57%) females and 451 (43%) males. Protenuria, hematuria, leucocyturia, nitrituria, and glucosuria were present in 18.9%, 1.7%, 9.2%, 1.8% and 2% of the subjects respectively. Proteinuria and haematuria was more prevalent in subjects aged ≥40 years (P < 0.05). The prevalence of leucocyturia, nitrituria, and glucosuria were independent of age (P < 0.05). There were no gender differences in the prevalence of urinary abnormalities (P < 0.05). Four hundred and forty-four (42.3%) of the cohort had hypertension (HTN). Proteinuria and leucocyturia were more prevalent in hypertensive subjects (P < 0.05) while hematuria, nitrituria, and glucosuria was independent of hypertensive status of subjects (P < 0.05). Conclusion: Urinary abnormalities are common among apparently healthy adults in Lagos. It is therefore recommended that it should be routinely done as a cheap screening tool and further evaluation conducted where necessary. This may result in cheaper treatment and better outcomes.
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Braimoh et al. (2016) conducted a cross-sectional in Apparently healthy (n=1,048). Urinalysis screening was evaluated on Prevalence of urinary abnormalities. Urinalysis screening among apparently healthy adults in Lagos revealed proteinuria in 18.9%, leucocyturia in 9.2%, glucosuria in 2.0%, nitrituria in 1.8%, and hematuria in 1.7%.
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