Rhythm control strategy in patients with atrial fibrillation in real clinical practice

Q: What is the clinical evidence from this study?

Study design: Observational. Population: Atrial fibrillation (n=10663). Intervention: Obesity vs. Patients without obesity. Primary outcome: Recurrence of atrial fibrillation after radiofrequency ablation (OR 4.4, 95% CI 1.31-14.51, p=0.03).

В. А. Ионин; E. L. Zaslavskaya; V. А. Pavlova; E. Yu. Petrischeva; O. I. Bliznuk; Georgi Borisov; D. S. Skuridin; Е. И. Баранова

doi:10.15275/annaritmol.2020.2.5

June 30, 2020Annaly aritmologiiOpen Access

Rhythm control strategy in patients with atrial fibrillation in real clinical practice

View Full Paper

Ask AI

Bookmark

Share

Key Points

To evaluate the prevalence of atrial fibrillation among hospitalized patients and assess the real-world utilization and effectiveness of antiarrhythmic therapy and catheter ablation.
Retrospectively analyzed 10,663 case histories of patients admitted to a therapeutic hospital between 2014 and 2018.
Evaluated arrhythmia symptom severity using the European Heart Rhythm Association (EHRA) scale and analyzed prior antiarrhythmic drug regimens and radiofrequency ablation outcomes.
Atrial fibrillation was present in 12.3% (1307/10,663) of hospitalized patients, and pre-hospital antiarrhythmic therapy was ineffective in 513/976 (52.6%) patients.
Radiofrequency ablation was effective in 67/105 (63.8%) patients, but arrhythmia recurrence was significantly more common in obese patients than non-obese patients (18/24 [75.0%] vs 16/27 [59.3%], p = 0.029; OR 4.4, 95% CI 1.31–14.51, p = 0.03).
Catheter ablation was not discussed in 79.0% of symptomatic patients without structural heart disease who failed prior drug therapy despite lacking absolute contraindications.

Study Design

Type

Observational (n=10,663)

Multicenter

No

PICO

P

Population

1,307 patients with atrial fibrillation (mean age 69.7 years, 56.2% female) identified from 10,663 retrospective case histories of patients hospitalized in a therapeutic clinic between 2014 and 2018.

E

Exposure / Comparator

Obesity vs Patients without obesity

O

Primary Outcome

Recurrence of atrial fibrillation after radiofrequency ablation — OR 4.4 (1.31-14.51), p=0.03

Main Result

Odds Ratio: 4.4 (95% CI 1.31–14.51)

Absolute Event Rate: 75% vs 59.3%

p-value: p=0.03

Limitations

Retrospective study design
Reliance on medical records for symptom assessment
Single-center study

Ask about this paper

Answers are grounded in this paper and cite their sources.

Abstract

Стратегия Контроля Ритма У Пациентов С Фибрилляцией

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Ионин et al. (2020) conducted an observational in Atrial fibrillation (n=10,663). Obesity vs. Patients without obesity was evaluated on Recurrence of atrial fibrillation after radiofrequency ablation (OR 4.4, 95% CI 1.31-14.51, p=0.03).

synapsesocial.com/papers/6aa21b2cd2b6e29a16d3cf06 https://doi.org/10.15275/annaritmol.2020.2.5

View Full Paper

Ask AI

Bookmark

Share

Rhythm control strategy in patients with atrial fibrillation in real clinical practice

Key Points

Study Design

PICO

Main Result

Limitations

Ask about this paper

Abstract

Discussion

Cite This Study

Rhythm control strategy in patients with atrial fibrillation in real clinical practice

Key Points

Study Design

PICO

Main Result

Limitations

Ask about this paper

Abstract

Discussion

Cite This Study

Keep reading

Keep reading