Key result
High-dose ibutilide (2 mg) was more effective than sotalol (1.5 mg/kg) in the conversion of atrial flutter to sinus rhythm (70% vs 19%).
Population
Intensive care patients with arrhythmias
Design
Review
Authors
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May inform ibutilide use for atrial flutter conversion in ICU; leaves open dedicated randomized trials in critically ill patients.
This review summarizes the management of arrhythmias in the intensive care unit, emphasizing the efficacy of amiodarone and ibutilide, the acceptability of rate control for AF, and the critical role of early defibrillation for cardiac arrest.
Trappe et al. (2003) conducted a review in Arrhythmias in intensive care patients. Antiarrhythmic agents and defibrillation was evaluated. High-dose ibutilide (2 mg) was more effective than sotalol (1.5 mg/kg) in the conversion of atrial flutter to sinus rhythm (70% vs 19%).
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