Key result
Paracetamol is an effective and safe alternative for pharmacological closure of patent ductus arteriosus in premature neonates, achieving a general success rate of 70-100%.
Why the study?
Does paracetamol improve the closure rate of patent ductus arteriosus in premature neonates?
Population
Premature neonates with hemodynamically significant patent ductus arteriosus and no contraindication for…
Design
Systematic_review
Authors
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Supports paracetamol for PDA closure in preterm neonates when NSAIDs contraindicated; reinforces Level-1 evidence for expanded use.
Does paracetamol improve the closure rate of patent ductus arteriosus in premature neonates?
Paracetamol is an effective and safe alternative for pharmacological closure of patent ductus arteriosus in premature neonates when NSAIDs are contraindicated or ineffective.
Khaleel I. ALSuwayfee (2016) conducted a review in Patent ductus arteriosus. Paracetamol vs. NSAIDs or none was evaluated on Successful closure of patent ductus arteriosus. Paracetamol is an effective and safe alternative for pharmacological closure of patent ductus arteriosus in premature neonates, achieving a general success rate of 70-100%.
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