Key result
Swine feces reveal ~12% HEV-3 prevalence, with HEV-3 and rotavirus A closely matching human isolates.
Why the study?
Pigs are frequently a major reservoir for zoonotic viral diseases, creating a need for periodic surveillance to determine infection rates in domestic pigs.
Cross-Sectional (n=296)
Yes
Swine HEV-3 and rotavirus A detected in domestic pigs are genetically closely related to human isolates, highlighting the potential risk of zoonotic transmission.
May signal zoonotic HEV-3 and rotavirus risk from swine; leaves open need for human surveillance studies.
The zoonotic transmission of viral diseases to humans is a serious public health concern.Pigs are frequently a major reservoir for several zoonotic viral diseases.Therefore, periodic surveillance is needed to determine the infection rates of zoonotic diseases in domestic pigs.Hepatitis E virus (HEV), rotavirus, sapovirus (SaV), and norovirus (NoV) are potential zoonotic viruses.In this study, 296 fecal samples were collected from weaned piglets and growing pigs in 13 swine farms, and the viral RNA was extracted.Partial viral genomes were amplified by reverse transcription-polymerase chain reaction (PCR) or nested-PCR using virusspecific primer sets under different PCR conditions.HEV-3, rotavirus A, and SaV genogoup 3 were detected from 11.5, 2.7, and 3.0% of the samples, respectively.On the other hand, NoV was not detected in any of the samples.Genetic analysis indicated that the nucleotide sequences of swine HEV-3 and rotavirus A detected in this study were closely related to those of human isolates.However, swine SaV was distant from the human strains.These results suggest that HEV-3 and rotavirus A can be transmitted from pigs to humans.Therefore, strict preventive measures should be implemented by workers in the swine industry to prevent infections with HEV-3 and rotavirus A excreted from pigs.
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Lyoo et al. (2020) conducted a cross-sectional in Zoonotic viral infections (n=296). Zoonotic viruses (HEV, rotavirus, sapovirus, norovirus) was evaluated on Prevalence of HEV-3, rotavirus A, and SaV. HEV-3, rotavirus A, and sapovirus genogroup 3 were detected in 11.5%, 2.7%, and 3.0% of swine fecal samples, respectively, with HEV-3 and rotavirus A showing close genetic relation to human isolates.
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