Key result
LMWH offers an acceptable alternative to warfarin for post-arthroplasty VTE prophylaxis due to predictable bioavailability.
Why the study?
What is the current status of anticoagulation therapy for preventing venous thromboembolism after total hip and total knee arthroplasty?
Population
Patients undergoing elective total hip and total knee arthroplasty
Design
Review
Authors
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LMWH may inform VTE prophylaxis choices after arthroplasty; leaves open updated randomized comparisons with current standards.
What is the current status of anticoagulation therapy for preventing venous thromboembolism after total hip and total knee arthroplasty?
Low-molecular-weight heparins provide an effective and more convenient alternative to warfarin for VTE prophylaxis following major orthopedic surgery.
Zimlich et al. (1996) conducted a review in Postoperative venous thromboembolism after elective total hip and total knee arthroplasty. Low-molecular-weight heparins vs. Warfarin was evaluated. Low-molecular-weight heparins are an acceptable alternative to warfarin for venous thromboembolism prophylaxis after total hip and knee arthroplasty, offering predictable bioavailability.
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