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November 20, 2025The Annals of Thoracic Surgery5 citationsOpen Access

Simplified Approach for Minimally Invasive Mitral Valve Surgery Through a Transaxillary Minithoracotomy Access

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PMPietro Giorgio MalvindiOBOlimpia BifulcoFSFrancesca Spagnolo

Key Result

Transaxillary minithoracotomy access for minimally invasive mitral valve surgery demonstrated excellent outcomes, including a 30-day mortality of 0.3% and a 6-year survival probability of 96%.

Study Design

Type

Cohort (n=615)

Multicenter

No

Structured PICO

Does minimally invasive mitral valve surgery through a right transaxillary minithoracotomy provide safe and effective outcomes in patients requiring mitral valve surgery?

P
Population
615 consecutive patients who underwent transaxillary mitral valve surgery from 2017 to 2024, with follow-up up to 6 years.
E
Exposure
Minimally invasive mitral valve surgery using right transaxillary minithoracotomy direct view access.
O
Outcome
30-day mortality and stroke or transient ischemic attack (TIA) rateshard clinical

A simplified minimally invasive transaxillary approach for mitral valve surgery demonstrates excellent perioperative safety, short recovery times, and durable long-term survival and valve function.

Abstract

BACKGROUND: Concerns still exist regarding increased technical complexity and longer operative times associated with minimally invasive cardiac procedures. To help overcoming this view and the skepticism about the value of performing cardiac surgery through reduced incisions, we present and discuss our experience with a simplified minimally invasive surgical setup using right transaxillary minithoracotomy direct view access. METHODS: This is a retrospective study that was based on an institutional database and included consecutive patients who underwent transaxillary mitral valve surgery from January 2017 to December 2024. RESULTS: The study included 615 patients. Mitral valve repair for degenerative disease was performed in 94% of patients, and tricuspid valve surgery was associated in 16%. Mean cardiopulmonary bypass and cross-clamp times were 105 ± 32 and 65 ± 23 minutes, respectively. Thirty-day mortality and stroke or transient ischemic attack rates were 0.3% and 0.9%, respectively. Median postoperative intubation time was 2 hours (interquartile range IQR, 0-6 hours), with 51% of patients extubated in the operating room. Median intensive care unit and hospital stays were 24 hours (IQR, 22-48 hours) and 7 days (IQR, 6-8 days), respectively. Residual mitral regurgitation was none or mild in 98% of patients who underwent repair procedures; recurrent moderate or greater regurgitation occurred in 1.4% of patients at 1 year and in 11% at 5 years. Survival probabilities at 1 and 6 years were 99% and 96%, respectively. CONCLUSIONS: Minimally invasive mitral surgery through the transaxillary approach ensures outstanding technical results with a low risk of perioperative complications. Increasing the perceived value of minimally invasive procedures through a simplified surgical setup can facilitate the initiation and wider adoption of a minimally invasive cardiac surgery program.

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Cite This Study

Malvindi et al. (2025) conducted a cohort in Mitral valve disease (n=615). Transaxillary minithoracotomy access for minimally invasive mitral valve surgery was evaluated on 30-day mortality. Transaxillary minithoracotomy access for minimally invasive mitral valve surgery demonstrated excellent outcomes, including a 30-day mortality of 0.3% and a 6-year survival probability of 96%.

synapsesocial.com/papers/6aa22aa9e308734d7dd30e15https://doi.org/10.1016/j.athoracsur.2025.10.037
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