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January 1, 1988American Heart JournalOpen Access

Left ventricular function in ischemic mitral regurgitation—A precatheterization assessment

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Why the study?

Does precatheterization assessment with physical examination and radionuclide angiography accurately diagnose mitral regurgitation in patients with unstable ischemic heart disease?

Population

150 patients with unstable ischemic heart disease

Design

Cross-sectional

Key result

Precatheterization assessment of regional wall motion abnormalities identified 26 of 29 patients with mitral regurgitation, improving diagnostic accuracy when combined with physical examination.

Authors

WBWarren M. BreisblattMCManuel D. CerqueiraCFCharlie K. Francis

Discussion

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Overview

May aid noninvasive MR detection in unstable ischemic disease when added to exam; leaves open need for prospective validation before clinical adoption.

Study Design

Type

Observational (n=150)

Structured PICO

Does precatheterization assessment with physical examination and radionuclide angiography accurately diagnose mitral regurgitation in patients with unstable ischemic heart disease?

P
Population
150 patients with unstable ischemic heart disease evaluated for the ability to diagnose mitral regurgitation using physical findings, ECG, and radionuclide angiography.
E
Exposure
Precatheterization assessment including physical findings, ECG, and radionuclide-determined global and regional left ventricular function
O
Outcome
Diagnosis of mitral regurgitation (MR)

Precatheterization assessment of regional wall motion abnormalities using radionuclide angiography, combined with physical examination, improves the diagnostic accuracy of identifying ischemic mitral regurgitation.

Cite This Study

Breisblatt et al. (1988) conducted an observational in unstable ischemic heart disease (n=150). Precatheterization assessment of left ventricular function with radionuclide angiography was evaluated on Diagnosis of mitral regurgitation. Precatheterization assessment of regional wall motion abnormalities identified 26 of 29 patients with mitral regurgitation, improving diagnostic accuracy when combined with physical examination.

synapsesocial.com/papers/6aa22dd453a31ffc17d3ce79https://doi.org/10.1016/0002-8703(88)90520-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Left Ventricular Mechanics in Functional Ischemic Mitral Regurgitation in Acute Inferoposterior Myocardial Infarction2016 · 8 citations
  2. 2Clinical presentation and prognosis of non valvular mitral regurgitation-A single institution experience2021
  3. 3Prognostic significance of mitral regurgitation after myocardial infarction: An echocardiography-based study2016
  4. 4Determinants of Functional Mitral Regurgitation Severity in Patients with Ischemic Cardiomyopathy versus Nonischemic Dilated Cardiomyopathy2013 · 9 citations
  5. 5Echocardiographic evaluation of left ventricular function in patients with mitral regurgitation: a meta-analysis2025