Key result
Males with HF, T2D, and obesity show higher LVMI, while females exhibit more renal dysfunction.
Cross-Sectional (n=111)
No
Absolute Event Rate: 142% vs 133.1%
p-value: p=<0.05
In patients with chronic heart failure and type 2 diabetes, disease manifestation differs by gender, with women more prone to renal dysfunction and anemia, and men more prone to adverse left ventricular remodeling.
Gender-specific LV changes in DM2-CHF may aid risk assessment; leaves open impact on therapy or outcomes.
Modern studies have shown that the prevalence of cardiovascular disease and chronic heart failure (CHF) specifically, in patients with diabetes mellitus (DM) is about 50%.Aim. To study gender-specific changes in laboratory indexes and structural myocardial parameters of left ventricle (LV) in CHF on the background of diabetes mellitus (DM) type 2. 111 patients with I–III functional class of disease with normal, overweight and abdominal obesity I–III degree were examined.Methods and results. Clinical and biochemical blood tests? glomerular filtration rate were used. Structural parameters of the myocardium were estimated with echocardiography. It is established that in CHF on the background of DM type 2 and obesity there is a tendency to develop anemia and renal dysfunction in women. Structural changes of the myocardium is more pronounced in men and presents the prevalence ofLV hypertrophy and dilatation of the heart cavities.Conclusion. This demonstrates different ways of negative impact of gender factor on the laboratory indexes and structural myocardial parameters in CHF on the background of DM type 2 and obesity.
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P. P. Bidzilya (2015) conducted a cross-sectional in Chronic heart failure with type 2 diabetes mellitus and obesity (n=111). Male gender vs. Female gender was evaluated on Left ventricular mass index (LVMI) (p=<0.05). Male patients with chronic heart failure, type 2 diabetes, and obesity demonstrated more pronounced structural myocardial changes including higher left ventricular mass index (142.0 vs 133.1 g/m2), whereas female patients had a higher tendency for anemia and renal dysfunction.
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