Key result
Type 1 diabetic adolescents show lower maximal workload versus healthy controls, worsening with higher HbA1.
Why the study?
Does the degree of metabolic control affect physical fitness in type I diabetic adolescents?
Case-Control (n=34)
Does the degree of metabolic control affect physical fitness in type I diabetic adolescents?
Effect estimate: r = -0.63
p-value: p=<0.01
Better metabolic control in type I diabetic adolescents is associated with improved physical fitness and maximal work capacity.
No immediate practice change for type 1 diabetic adolescents; leaves open whether better control improves fitness in prospective trials.
Seventeen type I male diabetic adolescents and 17 control subjects matched for age, height, and weight were submitted to maximal exercise on a bicycle ergometer. The diabetic subjects were divided into two groups according to their degree of metabolic control using total glycosylated hemoglobin (HbA1): group 1, diabetics with HbA1 less than 8.5% (n = 9) and group 2, diabetics with HbA1 greater than 8.5% (n = 8). Oxygen uptake, pulmonary ventilation, and heart rate were recorded at rest and at maximal load. Glucose, lactate, and free fatty acids were determined in blood before and after exercise. Maximal work load and oxygen uptake were significantly lower in the two diabetic groups than in the healthy controls. An inverse relationship was observed between HbA1 concentration and the maximal work load (r = -0.63; P less than 0.01). It can be concluded that diabetic adolescents should obtain the best possible degree of metabolic control to improve their performances.
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Poortmans et al. (1986) conducted a case-control in Type I Diabetes (n=34). Type I diabetes and degree of metabolic control (HbA1) vs. Healthy controls was evaluated on Maximal work load and oxygen uptake (r = -0.63, p=<0.01). Maximal work load was significantly lower in type I diabetic adolescents than healthy controls, and inversely correlated with HbA1 concentration (r = -0.63; P<0.01).
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