Evaluation of Skin and Subcutaneous Adipose Tissue Thickness for Optimal Insulin Injection

Materials and MethodsThe study was performed with patients with type 1 and type 2 diabetes aged 18 years or older, who were being followed-up by Istanbul Medeniyet University Goztepe Training and Research Hospital, Department of Internal Medicine and Diabetes Polyclinics, and healthy individuals as controls.Approval of the local ethics committee of the hospital and written informed consents from the subjects were obtained for the study.The diabetics group included patients with type 1 or type 2 diabetes mellitus diagnosed according to the American Diabetes Association (ADA) criteria [13] and the control group included healthy individuals who presented to the hospital for routine health checks and whose history did not include any known relevant diseases.Demographical and anthropometric data of the subjects who met the inclusion criteria and provided consents were recorded.The primary endpoint of the study sought to compare skin and subcutaneous adipose tissue thicknesses between diabetic patients and healthy controls.Skin thickness and subcutaneous adipose tissue thicknesses were evaluated by the type of diabetes and by whether the patient was on insulin therapy.The secondary endpoint aimed to assess the relationship between skin and subcutaneous adipose tissue thicknesses and BMI and waist circumference, for which a correlation analysis was performed. Anthropometric measurementsBody weight, waist circumference and height measurements were