Key result
In pregnant and postpartum women with suspected pulmonary embolism, the incidence of confirmed PE was low (15 of 375 episodes), and the absence of pleuritic chest pain demonstrated a negative predictive value of 97.8%.
Population
Pregnant women with suspected pulmonary embolism
Design
Cohort
Authors
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Should not yet alter imaging thresholds in suspected PE; leaves open pleuritic pain as a predictor pending prospective validation.
Observational (n=375)
No
Effect estimate: NPV 97.8% (95% CI 94.7-99.2)
Currently available clinical and laboratory tools cannot reliably exclude pulmonary embolism in pregnant patients, justifying the continued use of imaging despite radiation risks.
Scott et al. (2011) conducted an observational in Suspected pulmonary embolism (n=375). Clinical and laboratory assessment for suspected pulmonary embolism was evaluated on Negative predictive value of the absence of pleuritic chest pain for excluding pulmonary embolism (NPV 97.8%, 95% CI 94.7-99.2). In pregnant and postpartum women with suspected pulmonary embolism, the incidence of confirmed PE was low (15 of 375 episodes), and the absence of pleuritic chest pain demonstrated a negative predictive value of 97.8%.
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