Key result
Pregnancy-adapted algorithms like the YEARS criteria and revised Geneva rule can safely exclude suspected pulmonary embolism without imaging in up to one-third and 14% of pregnant patients, respectively.
Why the study?
Excluding PE in pregnant patients has typically necessitated diagnostic imaging despite low disease prevalence, prompting evaluation of whether pregnancy-adapted clinical prediction rules with D-dimer testing can safely avoid imaging.
Do pregnancy-adapted algorithms with D-dimer testing reduce the need for diagnostic imaging in pregnant patients with suspected pulmonary embolism?
Do pregnancy-adapted algorithms with D-dimer testing reduce the need for diagnostic imaging in pregnant patients with suspected pulmonary embolism?
Pregnancy-adapted clinical prediction rules combined with D-dimer testing can safely reduce the need for radiation-based diagnostic imaging in a subset of pregnant patients with suspected pulmonary embolism.
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May reduce imaging in pregnant patients with suspected PE using YEARS criteria; hypothesis-generating and requires prospective validation.
Wee‐Shian Chan (2020) conducted a review in Suspected pulmonary embolism in pregnancy. Pregnancy-adapted algorithms (YEARS criteria and revised Geneva rule) vs. Diagnostic imaging was evaluated. Pregnancy-adapted algorithms like the YEARS criteria and revised Geneva rule can safely exclude suspected pulmonary embolism without imaging in up to one-third and 14% of pregnant patients, respectively.
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