Hypertension prevalence, incidence and risk factors among children and adolescents in Africa: a systematic review and meta-analysis protocol
Key result
Protocol outlines an upcoming meta-analysis on hypertension prevalence and risk factors in African youth.
Why the study?
What is the prevalence, incidence, and risk factors of hypertension among children and adolescents in Africa?
Population
Children and adolescents in Africa
Design
Systematic_review
Authors
Discussion
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Overview
Protocol for African pediatric hypertension meta-analysis; leaves open prevalence estimates and risk stratification until results emerge.
Key Points
- To outline a systematic review and meta-analysis protocol for establishing accurate estimates of hypertension prevalence, incidence, and associated risk factors among children and adolescents in Africa.
- Follows MOOSE guidelines to search PubMed, Google Scholar, HINARI, and African journals for English and French publications between January 1, 1985, and July 31, 2015.
- Pools study-specific estimates of hypertension prevalence and incidence using a random-effects meta-analysis model in R, stratified by central, eastern, northern, southern, and western African regions.
- Evaluates between-study heterogeneity using the chi-square test on Cochrane's Q statistic and detects publication bias via funnel plots and Egger's test.
- Empirical prevalence and incidence rates are not yet reported because this publication is an analytical protocol.
- Planned analyses will yield regional and overall pooled summary estimates of pediatric hypertension across Africa.
- Risk factor associations will be quantitatively evaluated, defining statistically significant predictors of hypertension at p < 0.05.
Study Design
Type
Systematic Review
Structured PICO
What is the prevalence, incidence, and risk factors of hypertension among children and adolescents in Africa?
P
Population
A protocol for a systematic review and meta-analysis to assess the prevalence, incidence, and risk factors of hypertension among children and adolescents in Africa.
O
Outcome
Prevalence and incidence of hypertension, and association between risk factors and hypertension
This protocol outlines a systematic review and meta-analysis to determine the prevalence, incidence, and risk factors of hypertension in African children and adolescents.
Cite This Study
Essouma et al. (2015) conducted a systematic review in Hypertension. Risk factors was evaluated on Prevalence and incidence of hypertension, and association with risk factors. This paper describes a protocol for a systematic review and meta-analysis to evaluate the prevalence, incidence, and risk factors of hypertension among children and adolescents in Africa.