Case report demonstrates fatal irreversible pancytopenia in an immunocompetent adult, highlighting the risk of fulminant bone marrow failure from cytomegalovirus.
A case of severe and irreversible pancytopenia secondary to acute primary cytomegalovirus infection in an immunocompetent woman is described. The patient presented with thrombocytopenia, lymphopenia, anemia, and abnormal liver function tests. Treatment with corticosteroids and intravenous immunoglobulin was ineffective in reconstituting hemopoiesis. The patient developed severe sepsis and eventually expired.
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Koukoulaki et al. (2010) studied this question.
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