Why the study?
Esophageal thermal injury remains a major risk during posterior left atrial ablation, and whether a dedicated proactive esophageal cooling device is feasible and comparable to standard luminal esophageal temperature monitoring with reactive cold-water instillation was unstudied.
Does proactive esophageal cooling using a dedicated device reduce esophageal mucosal damage compared to reactive cooling in patients undergoing catheter ablation for atrial fibrillation?
Population
6 patients undergoing catheter ablation for AF
Comparison
Dedicated esophageal cooling device vs standard LET monitoring with reactive cold-water instillation
Design
Randomized study
Follow-up
3 months
Key result
Proactive esophageal cooling during atrial fibrillation ablation resulted in 1 of 3 patients developing a grade 2a lesion, compared to 2 of 3 patients receiving reactive cooling.
Authors
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Proactive cooling may reduce esophageal injury in AF ablation; extends feasibility data and supports larger confirmatory RCTs.
RCT (n=6)
randomized
No
Does proactive esophageal cooling using a dedicated device reduce esophageal mucosal damage compared to reactive cooling in patients undergoing catheter ablation for atrial fibrillation?
Proactive esophageal cooling using a dedicated device is feasible during atrial fibrillation ablation and provides a basis for further investigation into its efficacy for esophageal protection compared to reactive cooling.
Clark et al. (2022) conducted an RCT in Atrial fibrillation (n=6). Proactive esophageal cooling device vs. Standard luminal esophageal temperature monitoring with reactive cold-water instillation was evaluated on Esophageal mucosal damage assessed by esophagogastroduodenoscopy. Proactive esophageal cooling during atrial fibrillation ablation resulted in 1 of 3 patients developing a grade 2a lesion, compared to 2 of 3 patients receiving reactive cooling.