Key result
Obesity is linked to higher BP and larger end-diastolic and end-systolic volumes.
Why the study?
Obesity contributes to cardiovascular risk factors and adverse cardiac events, but its impact on various cardiovascular parameters required further assessment.
Does obesity impact cardiac volumes and left ventricular diameter in adults with suspected heart disease?
Cross-Sectional (n=105)
No
Does obesity impact cardiac volumes and left ventricular diameter in adults with suspected heart disease?
Obesity is significantly associated with elevated blood pressure and larger cardiac volumes in patients with suspected heart disease.
Answers are grounded in this paper and cite their sources.
Obesity-linked BP elevation and larger LV volumes should not yet change practice; hypothesis-generating for prospective studies on causality and intervention.
Introduction. Obesity, a pressing global health issue worldwide, contributes to risk factors such as hypertension and dyslipidemia, creating an unfavorable cardiovascular environment and increasing the likelihood of adverse cardiac events. His study aims to assess the impact of obesity on various cardiovascular parameters. Methods. A cross‐sectional analysis was conducted at a Heart Center, focusing on adults admitted for suspected heart diseases. The dataset included information on demographics, clinical history, laboratory results, and echocardiography. Descriptive analysis and multiple linear regression were employed using IBM SPSS Statistics version 26. Results. The study of 105 individuals with suspected heart diseases revealed prevalent health factors such as hypertension (47.6%) and hyperlipidemia (61%). Body mass index (BMI) averaged 30, indicating a trend toward overweight. Obesity significantly associated with higher systolic blood pressure (SBP, p = 0.005) and diastolic blood pressure (DBP, p = 0.002), larger cardiac volumes (end‐diastolic volume, EDV, p = 0.013; end‐systolic volume, ESV, p = 0.040), and a marginally significant influence on left ventricular end‐diastolic diameter (LVEDD, p = 0.068). No significant associations were found with left ventricular end‐systolic diameter (LVEDS), heart rate (HR), or ejection fraction (EF). Conclusions. Our study highlights a significant association between obesity and elevated blood pressure, larger cardiac volumes, and a marginal impact on left ventricular end‐diastolic diameter. While caution is needed in inferring causation due to the study’s cross‐sectional nature, these findings underscore the importance of addressing obesity as a potential risk factor for adverse cardiovascular outcomes. Further investigations are warranted to enhance our understanding of the complex interplay between obesity and cardiovascular health.
No takes yet. Share an insight, caveat, or question.
Omidi et al. (2024) conducted a cross-sectional in suspected heart diseases (n=105). Obesity was evaluated on cardiac volumes (end-diastolic volume and end-systolic volume) and blood pressure (p=0.013). Obesity was significantly associated with higher systolic blood pressure (p=0.005), diastolic blood pressure (p=0.002), and larger end-diastolic (p=0.013) and end-systolic (p=0.040) volumes.
Synapse has enriched 10 related papers. Consider them for comparative context: