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March 14, 2023Journal of Taibah University Medical SciencesOpen Access

Effects of physical activity breaks during prolonged sitting on vascular and executive function—A randomised cross-over trial

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Key result

Physical activity breaks during 4 hours of prolonged sitting mitigated the significant decreases in reaction time (-30.59%) and accuracy (-10.56%) observed with uninterrupted sitting.

Why the study?

High sedentary behaviour is linked to adverse effects on vascular and cognitive function, but evidence regarding the efficacy of workplace sitting interventions remains lacking.

Do physical activity breaks during prolonged sitting improve vascular and executive function in healthy adults?

Comparison

Uninterrupted sitting vs sitting with hourly walking breaks vs sitting with hourly stair climbing breaks

Design

Randomised cross-over trial

Follow-up

4 h

Authors

OCObhuli ChandranPPPoovitha Shruthi PSSSuresh Sukumar

Discussion

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Overview

Activity breaks may preserve cognition during prolonged sitting; hypothesis-generating for cardiometabolic benefits, requiring larger trials.

Study Design

Type

RCT (n=21)

Randomization

Cross-over

Structured PICO

Do physical activity breaks during prolonged sitting improve vascular and executive function in healthy adults?

P
Population
21 healthy adults who completed 4 hours of simulated work conditions with and without physical activity breaks.
I
Intervention
Sitting interrupted by 3 min of walking every hour (LIT) or 3 min of stair climbing every hour (MIT) during 4 hours of simulated work conditions
C
Comparator
Uninterrupted sitting (SIT) for 4 hours
O
Outcome
Carotid (CA) and superficial femoral artery (SFA) diameter, velocity, shear rate and blood flow measured at hours 0, 2 and 4, and executive function assessed every hoursurrogate

Brief physical activity breaks during prolonged sitting mitigate declines in cognitive function but do not acutely improve vascular function.

Limitations

  • Short-term study duration
  • Conducted in a simulated work environment rather than a natural environment
  • short term study
  • not conducted in natural environment

Cite This Study

Chandran et al. (2023) conducted an RCT in Healthy adults (n=21). Physical activity breaks (walking or stair climbing) vs. Uninterrupted sitting was evaluated on Reaction time and accuracy. Physical activity breaks during 4 hours of prolonged sitting mitigated the significant decreases in reaction time (-30.59%) and accuracy (-10.56%) observed with uninterrupted sitting.

synapsesocial.com/papers/6aa26cbe74fc654bd03231a8https://doi.org/10.1016/j.jtumed.2023.03.004
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