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October 1, 1995Molecular and Cellular BiologyOpen Access

The Pentapeptide Motif of Hox Proteins Is Required for Cooperative DNA Binding with Pbx1, Physically Contacts Pbx1, and Enhances DNA Binding by Pbx1

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Authors

PKPaul S. KnoepflerUniversity of California, DavisMKMark P. KampsUniversity of California, San Diego

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Cite This Study

Knoepfler et al. (1995) studied this question.

synapsesocial.com/papers/6aa26cd64f988c8b52139fefhttps://doi.org/10.1128/mcb.15.10.5811
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Also Consider

Synapse has enriched 4 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor1990 · 680 citations
  2. 2Crystal structure of a MATα2 homeodomain-operator complex suggests a general model for homeodomain-DNA interactions1991 · 535 citations
  3. 3Fusion with E2A converts the Pbx1 homeodomain protein into a constitutive transcriptional activator in human leukemias carrying the t(1;19) translocation.1994 · 125 citations
  4. 4Mice homozygous for a targeted disruption of Hoxd-3 (Hox-4.1) exhibit anterior transformations of the first and second cervical vertebrae, the atlas and the axis1993 · 228 citations