What is the clinical evidence from this study?

Study design: Editorial. Population: Atrial fibrillation. Intervention: Oral anticoagulants (OACs). Primary outcome: Rate of OAC use in eligible patients (CHADS2 score ≥2) in 2017.

April 9, 2020Circulation JournalOpen Access

National Health Insurance Database and Atrial Fibrillation Research

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Key result

In 2017, 83% of eligible patients with a CHADS2 score ≥2 were on oral anticoagulants, with direct oral anticoagulants accounting for 60% of this use.

Structured PICO

Population

An editorial discussing a regional Japanese database study on the prevalence of non-valvular atrial fibrillation and temporal trends in oral anticoagulant use among patients under 75 years of age.

Exposure

Oral anticoagulant (OAC) use

Outcome

Temporal trends of AF prevalence and rate of oral anticoagulant (OAC) use

Limitations

NHI data are not primarily collected for research purposes, requiring validation of claims-based diagnoses
Participants aged ≥75 years were excluded because they switched to the late-elderly health insurance system
The studied populations may not be representative of the general Japanese population
Subjective bleeding risks, patient preferences, and contraindications are rarely captured in NHI data
Did not report incidence rates of AF

Discussion

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Implication

This editorial discusses a study on the temporal trends of AF prevalence and OAC use in Japan, highlighting the role of an aging population in increasing AF prevalence.

Cite This Study

Eiichi Watanabe (2020) conducted an editorial in Atrial fibrillation. Oral anticoagulants (OACs) was evaluated on Rate of OAC use in eligible patients (CHADS2 score ≥2) in 2017. In 2017, 83% of eligible patients with a CHADS2 score ≥2 were on oral anticoagulants, with direct oral anticoagulants accounting for 60% of this use.

synapsesocial.com/papers/6aa26e91da8566d019e566da https://doi.org/10.1253/circj.cj-20-0241

Topics

Atrial fibrillation Persistent AF management Anticoagulation in AF

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Implication

This editorial discusses a study on the temporal trends of AF prevalence and OAC use in Japan, highlighting the role of an aging population in increasing AF prevalence.