Key result
Lowest educational class linked to ~64% higher CVD mortality in men, improving SCORE risk discrimination.
Why the study?
Does the addition of educational class to the SCORE risk equation improve the accuracy of cardiovascular disease risk prediction in adults aged 40-64 free from baseline CHD?
Cohort (n=68,455)
Yes
Does the addition of educational class to the SCORE risk equation improve the accuracy of cardiovascular disease risk prediction in adults aged 40-64 free from baseline CHD?
Hazard Ratio: 1.64 (95% CI 1.42–1.9)
Incorporating educational class into the SCORE risk equation improves cardiovascular mortality risk prediction and classification in men, particularly in Nordic and Eastern European countries, which could enhance social equity in primary prevention.
No takes yet. Share an insight, caveat, or question.
Educational class may refine SCORE discrimination in cohorts; leaves open prospective validation and equity impact.
Ferrario et al. (2014) conducted a cohort in Cardiovascular disease (n=68,455). Lowest educational class vs. Higher educational classes was evaluated on CVD mortality (HR 1.64, 95% CI 1.42 to 1.90). The lowest educational class was associated with higher CVD mortality in men (HR 1.64; 95% CI 1.42-1.90) and women (HR 1.31; 95% CI 1.02-1.68), improving risk discrimination when added to SCORE.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: