Key result
Reduced physical activity in healthy young adults was associated with significantly higher central aortic systolic blood pressure (115.56 vs 105.13 mmHg), plasma atherogenic index, and sICAM-1.
Why the study?
Does reduced physical activity increase arterial stiffness, atherogenic index, and soluble adhesion molecules in healthy young adults?
Observational (n=54)
Does reduced physical activity increase arterial stiffness, atherogenic index, and soluble adhesion molecules in healthy young adults?
Absolute Event Rate: 115.56% vs 105.13%
Reduced physical activity in healthy young adults is associated with increased arterial stiffness, atherogenic index, and soluble adhesion molecules, which may accelerate the atherogenic process.
Reduced activity may worsen early vascular-metabolic markers in young adults; leaves open causal impact and need for intervention trials.
OBJECTIVE: To examine some anthropometric parameters, arterial stiffness, lipid profile, and soluble adhesion molecules in young adults with reduced physical activity. MATERIAL AND METHODS: The study is carried on 54 healthy young adults aged 20.97 ± 2.04 years. Two groups: 23 with reduced physical activity (INAC) and 31 with optimal physical activity (AC). Body mass index (BMI), basal metabolic rate (BMR), central aortic systolic blood pressure (CSBP, mmHg), plasma atherogenic index (AIP), and serum soluble cell adhesion molecules (sICAM-1, sVCAM-1) are followed up. RESULTS: CSBP [115.56 ± 10.22 vs. 105.13 ± 9.88*], AIP [-0.04 ± 0.18 vs. -0.08 ± 0.08**] and sICAM-1 [362.5 ± 49.95 vs. 281.75 ± 80.39**] are significantly higher, and BMR [1431 ± 297.9 vs. 1674.6 ± 365.57*] is significantly lower in the physically inactive young healthy adults. CONCLUSIONS: CSBP, AIP, and sICAM-1 are higher in young adults with reduced physical activity. This plays substantial role in the acceleration of atherogenic process and in long-term perspective could promote cardiovascular diseases.
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Bacelova et al. (2017) conducted an observational in Healthy young adults (n=54). Reduced physical activity vs. Optimal physical activity was evaluated on Central aortic systolic blood pressure (CSBP, mmHg). Reduced physical activity in healthy young adults was associated with significantly higher central aortic systolic blood pressure (115.56 vs 105.13 mmHg), plasma atherogenic index, and sICAM-1.
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