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September 10, 2026Acta cardiologica. Supplementum

Aortic aneurysm from 1990 to 2021: a falling rate is not a falling burden

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Authors

TMThibault-Marie Azevedo MendesMMManuel Azevedo MendesSBSamuel Brüls

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Overview

Epidemiological analysis reveals diverging incidence rates and total disease burden in aortic aneurysm, highlighting persistent public health risks despite improved age-standardized rates.

Key Points

  • Evaluate global epidemiological patterns, mortality rates, and overall public health burden associated with aortic aneurysm between 1990 and 2021.
  • Assessed global trends in aortic aneurysm incidence, prevalence, and mortality spanning 1990 through 2021.
  • Evaluated natural history outcomes, focusing on asymptomatic clinical progression and out-of-hospital death rates following acute rupture.
  • Age-standardized rates have decreased over time, yet the absolute number of cases and overall burden have increased due to population growth and aging demographics.
  • Aortic aneurysm typically progresses without symptoms, with acute rupture associated with an out-of-hospital mortality rate exceeding 80%.

Cite This Study

Mendes et al. (2026) studied this question.

synapsesocial.com/papers/6aa27ad858559d80afc73bc6https://doi.org/10.1080/00015385.2026.2728405
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