PulseTrendingJournal ClubResearchersJournalsExplore
Instagram
HomeTrendingJournal ClubExplore
Synapse
⌘+K
Synapse
September 10, 2026The Journal of Cardiovascular Nursing

Mediators of the Effect of an Educational Intervention on Health-Related Quality of Life in Patients With Heart Failure

View Full Paper
Ask AI
Bookmark
Share

Why the study?

Although nursing interventions improve heart failure outcomes, the mechanisms underlying their effects on health-related quality of life remain unclear.

Does an educational intervention improve health-related quality of life in patients with heart failure?

Comparison

Individual education plus 8 weeks of telephone follow-up vs usual care

Design

Causal mediation analysis of a randomized controlled trial

Follow-up

6 months

Key result

An educational intervention improved health-related quality of life in heart failure patients, mediated by overall self-care (indirect effect -7.18; 95% CI -13.48 to -2.35).

Authors

BHBoyoung HwangYJYujin JeongHCHyun-Jai Cho

Discussion

Loading...

Member takes

Overview

Prioritize self-care in heart failure education to improve HRQOL; confirms its causal mediation in this RCT.

Key Points

  • To determine whether heart failure knowledge, self-care behaviors, self-care confidence, or social support mediate the effect of an educational intervention on health-related quality of life.
  • Analyzed data from a randomized controlled trial comparing an individual education program with 8 weeks of telephone follow-up (n = 60) against usual care (n = 62) in patients with heart failure.
  • Conducted causal mediation analysis adjusting for age, sex, and baseline scores to evaluate potential 3-month mediators on 6-month health-related quality of life outcomes.
  • Intervention assignment was significantly associated with heart failure knowledge, overall self-care, self-care maintenance, self-care management, and self-care confidence at 3 months (all P < .05).
  • Overall self-care (indirect effect -7.18, 95% CI -13.48 to -2.35) and self-care maintenance (indirect effect -3.02, 95% CI -7.94 to -0.07) showed significant indirect effects on 6-month overall and physical health-related quality of life.
  • No evaluated mediator demonstrated a statistically significant indirect effect on emotional health-related quality of life.

Study Design

Type

RCT (n=122)

Structured PICO

Does an educational intervention improve health-related quality of life in patients with heart failure?

P
Population
122 patients with heart failure randomized to an educational intervention or usual care, followed for 6 months to assess mediators of health-related quality of life.
I
Intervention
Individual education plus 8 weeks of telephone follow-up
C
Comparator
Usual care
O
Outcome
Health-related quality of life (HRQOL) at 6 monthspatient reported

Main Result

Effect estimate: indirect effect -7.18 (95% CI -13.48 to -2.35)

Educational interventions improve health-related quality of life in heart failure patients primarily by enhancing overall self-care and self-care maintenance.

Cite This Study

Hwang et al. (2026) conducted an RCT in Heart failure (n=122). Educational intervention (individual education plus telephone follow-up) vs. Usual care was evaluated on Health-related quality of life at 6 months mediated by overall self-care (indirect effect -7.18, 95% CI -13.48 to -2.35). An educational intervention improved health-related quality of life in heart failure patients, mediated by overall self-care (indirect effect -7.18; 95% CI -13.48 to -2.35).

synapsesocial.com/papers/6aa27bcf58559d80afc754b8https://doi.org/10.1097/jcn.0000000000001385
View Full Paper
Ask AI
Bookmark
Share