Answers are grounded in this paper and cite their sources.
The equilibrium solubilities of five nitrogen-containing drugs carbamazepine, diazepam, codeine, atropine, and lorazepam have been measured in supercritical carbon dioxide using a simple and reliable static method. The measurements were performed in the pressure range (122 to 355) bar at the temperatures (308, 318, 328, 338, and 348) K. The measured solubilities were correlated using a semiempirical model. The calculated results show satisfactory agreement with experimental data.
No takes yet. Share an insight, caveat, or question.
Yamini et al. (2001) studied this question.
Synapse has enriched 10 related papers. Consider them for comparative context: