Key result
Echocardiographic diagnosis of MVP in panic disorder varies by ~60% depending on expert reader criteria.
Why the study?
Does the choice of echocardiographic criteria affect the diagnosed prevalence of mitral valve prolapse in patients with panic disorder?
Cross-Sectional (n=15)
Does the choice of echocardiographic criteria affect the diagnosed prevalence of mitral valve prolapse in patients with panic disorder?
The prevalence of mitral valve prolapse in patients with panic disorder is highly dependent on the specific echocardiographic criteria used by the reader.
Answers are grounded in this paper and cite their sources.
MVP diagnosis in panic disorder varies markedly by echocardiographic criteria; leaves open any true association and requires standardized methods in future studies.
Although several investigators have found a higher incidence of mitral valve prolapse (MVP) in patients with panic disorder (PD) and agoraphobia with panic attacks (AgP), there are now several conflicting reports. Discrepancy in the rate of echocardiographic diagnosis of MVP in PD/AgP may be due to different criteria used in evaluating the echocardiogram. In this study, 15 echocardiograms performed on patients with PD/AgP were evaluated by two separate expert echocardiographers. Each used his own standard criteria for diagnosing MVP. The first reader diagnosed MVP in 9 of 15 patients with PD/AgP while the second did not diagnose MVP in any of the 15 patients. This substantiates the belief that criteria variance strongly influences estimates of the prevalence of MVP among patients with PD/AgP.
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Shear et al. (1986) conducted a cross-sectional in Panic disorder and agoraphobia with panic attacks (n=15). Echocardiographic criteria for diagnosing MVP vs. Alternative echocardiographic criteria was evaluated on Diagnosis of mitral valve prolapse. Echocardiographic diagnosis of mitral valve prolapse in patients with panic disorder varied from 60% to 0% depending on the specific criteria used by two different expert readers.
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