Key result
Sentinel cerebral embolic protection facilitates WATCHMAN LAAC in AF patients with persistent LAA thrombus.
Why the study?
The presence of a left atrial appendage thrombus is a contraindication for percutaneous LAAC, but persistent thrombus remains not uncommon despite oral anticoagulation.
Does transcatheter cerebral embolic protection allow for safe left atrial appendage closure in patients with persistent LAA thrombus?
Case Report (n=2)
Does transcatheter cerebral embolic protection allow for safe left atrial appendage closure in patients with persistent LAA thrombus?
Transcatheter cerebral embolic protection may facilitate left atrial appendage closure in patients with persistent LAA thrombus, a condition that is typically a contraindication for the procedure.
Answers are grounded in this paper and cite their sources.
May enable LAA closure despite persistent thrombus; hypothesis-generating and requires prospective validation.
Percutaneous left atrial appendage closure (LAAC) has been increasingly used in patients with atrial fibrillation who are poor candidates for long-term oral anticoagulation. The presence of a left atrial appendage (LAA) thrombus is a contraindication for percutaneous LAAC. Despite oral anticoagulation, persistent thrombus is not uncommon. We describe the use of transcatheter cerebral embolic protection with the Sentinel cerebral protection system during LAAC using WATCHMAN in two atrial fibrillation patients who had persistent LAA thrombus despite oral anticoagulation.
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Tan et al. (2020) conducted a case report in Atrial fibrillation with persistent left atrial appendage thrombus (n=2). Transcatheter cerebral embolic protection (Sentinel system) during WATCHMAN procedure was evaluated. Transcatheter cerebral embolic protection with the Sentinel system was used during WATCHMAN left atrial appendage closure in two atrial fibrillation patients with persistent LAA thrombus.
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