Key result
Surgical treatment of myxofibrosarcomas resulted in a 43% rate of positive margins, 14% local recurrence, and 30% metastasis, with microscopic spread up to 29 mm beyond macroscopic tumor.
Population
50 patients with primary or recurrent myxofibrosarcoma treated surgically between 1997 and 2012, median age…
Design
Cohort
Follow-up
Mean 21 months for local recurrence, 17 months for…
Authors
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May support wider resection margins in myxofibrosarcoma; leaves open optimal width for prospective trials.
Observational (n=50)
No
High rates of positive margins and microscopic spread up to 29 mm beyond macroscopic tumor in myxofibrosarcoma highlight the need for multidisciplinary surgical management.
Ghazala et al. (2016) conducted an observational in Myxofibrosarcoma (n=50). Surgical resection was evaluated on Positive margins, local recurrence, and metastases. Surgical treatment of myxofibrosarcomas resulted in a 43% rate of positive margins, 14% local recurrence, and 30% metastasis, with microscopic spread up to 29 mm beyond macroscopic tumor.
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