Key result
Two infants who developed severe neurogenic pulmonary edema following febrile seizures fully recovered without sequelae after prompt intensive respiratory management.
Case Report (n=2)
Neurogenic pulmonary edema is a rare but severe complication of febrile seizures in early childhood that can be successfully managed with prompt respiratory support.
May support prompt respiratory support for neurogenic pulmonary edema in febrile seizures; case reports leave generalizability and incidence open.
Neurogenic pulmonary edema (NPE) is a clinical entity that can occur following central nervous system disorders. However, NPE occurs quite rarely in early childhood, and there has only been one report about pediatric NPE associated with febrile seizures. Two cases are reported here. One case involved a 2-year-old girl who presented with febrile seizures, which rapidly progressed to severe NPE. Since the NPE occurred in the emergency department room, the patient was able to be resuscitated via immediate endotracheal intubation. The other case involved an 11-month-old boy who developed respiratory distress following a 50-min episode of febrile status epilepticus. Both patients required respiratory management in the intensive care unit. However their conditions were dramatically improved within several days and fully recovered without any sequelae.
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Tasaka et al. (2016) conducted a case report in Neurogenic pulmonary edema following febrile seizures (n=2). Intensive respiratory management was evaluated on Recovery from neurogenic pulmonary edema. Two infants who developed severe neurogenic pulmonary edema following febrile seizures fully recovered without sequelae after prompt intensive respiratory management.
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