Intracoronary Thrombolysis for Acute Myocardial Infarction

Editorials1 January 1982Intracoronary Thrombolysis for Acute Myocardial InfarctionSHELDON GOLDBERG, M.D., PETER R. MAROKO, M.D., TOBY R. ENGEL, M.D.SHELDON GOLDBERG, M.D., PETER R. MAROKO, M.D., TOBY R. ENGEL, M.D.Author, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-96-1-115 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptRecent observations have prompted reexamination of our concepts concerning optimal therapy for myocardial infarction. Rentrop and associates have shown the acutely occluded coronary artery could be recanalized safely in many patients with acute myocardial infarction by intracoronary administration of streptokinase (1). This observation, when considered with that of DeWood and associates (2), who showed by angiography that complete obstruction to coronary flow caused by thrombosis occurs in nearly 90% of patients in the early hours of myocardial infarction, strongly suggests that intracoronary thrombolysis has important therapeutic potential. The medical community received the first reports about this promising therapeutic technique with...References1. RENTROPBLANKEKARSCHKAISERKOSTERINGLEITZ PHKHHK. Selective intracoronary thrombolysis in acute myocardial infarction and unstable angina pectoris. Circulation, 1981;63:307-17. CrossrefMedlineGoogle Scholar2. DEWOODSPORESNOTSKE MJR. Prevalence of total coronary occlusion during the early hours of transmural myocardial infarction. N Engl J Med. 1980;303:897-902. CrossrefMedlineGoogle Scholar3. FISHBEINHAREGISSENSPADAROMACLEANMAROKO MCSJDP. 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Author, Article, and Disclosure InformationAffiliations: The Medical College of Pennsylvania Philadelphia, Pennsylvania PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited ByThrombolysis in Acute Myocardial InfarctionShould coronary artery bypass be delayed following successful direct coronary artery streptokinase thrombolysis during evolving myocardial infarction?Myeloperoxidase activity as a quantitative assessment of neutrophil infiltration into ischemie myocardiumIntracoronary thrombolysis in acute myocardial infarction: Clinical course following successful myocardial reperfusionThrombolysis in acute myocardial infarction: treatment of the underlying coronary artery disease.Trials of New MethodsDAVID H. SPODICK, M.D., D.SC. 1 January 1982Volume 96, Issue 1Page: 115-117KeywordsAcute myocardial infarctionAngiographyCoronary arteriesMyocardial infarctionThrombosis Issue Published: 1 January 1982 PDF DownloadLoading ...