Key result
High intraoperative FiO2 fails to reduce surgical site infections compared to low FiO2.
Why the study?
Controversies remain regarding optimal intraoperative FiO2, as WHO recommended 80% FiO2 to reduce surgical site infections despite data suggesting hyperoxia may have adverse effects.
Does intraoperative high FiO2 reduce surgical site infection in adult patients undergoing anaesthesia?
Systematic Review
Does intraoperative high FiO2 reduce surgical site infection in adult patients undergoing anaesthesia?
The systematic administration of high intraoperative FiO2 to decrease surgical site infections or improve perioperative outcomes is unjustified based on current evidence.
No takes yet. Share an insight, caveat, or question.
High FiO2 should not be used routinely to prevent surgical site infection; challenges prior recommendations and supports standard oxygen strategies.
Fasquel et al. (2020) conducted a systematic review in Patients undergoing general or regional anaesthesia. High inspiratory oxygen fraction (FiO2) vs. Low inspiratory oxygen fraction (FiO2) was evaluated on Surgical site infection (SSI). Intraoperative high inspiratory oxygen fraction (FiO2) did not reduce the incidence of surgical site infection compared to low FiO2 during general or regional anaesthesia.
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