Why the study?
To determine whether high perioperative inspired oxygen fraction (FiO2) compared with low FiO2 has more deleterious postoperative clinical outcomes in patients undergoing non-thoracic surgery under general anesthesia.
Does high perioperative FiO2 compared to low FiO2 affect mortality and pulmonary outcomes in patients undergoing non-thoracic surgery under general anesthesia?
Does high perioperative FiO2 compared to low FiO2 affect mortality and pulmonary outcomes in patients undergoing non-thoracic surgery under general anesthesia?
High perioperative FiO2 does not affect short-term mortality compared to low FiO2 in non-thoracic surgery patients, but may increase the incidence of postoperative atelectasis.
Authors
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No mortality difference with high vs low perioperative FiO2; confirms equivalence and supports minimizing hyperoxia in non-thoracic surgery.
Lim et al. (2021) studied this question.
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