Porphyria: Clinical Observations and a Family Vignette

Case Reports1 March 1951PORPHYRIA: CLINICAL OBSERVATIONS AND A FAMILY VIGNETTEGEORGE L. CALVY, E. J. JARUSZEWSKI, H. H. CARROLL, F.A.C.P.GEORGE L. CALVYSearch for more papers by this author, E. J. JARUSZEWSKISearch for more papers by this author, H. H. CARROLL, F.A.C.P.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-34-3-767 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptPorphyria presents a varied clinical picture of abdominovisceral, neurologic and cutaneous involvement in association with increased excretion of porphyrins in the urine and feces. The diagnosis is to be entertained whenever passage of dark, red or mahogany colored urine is cited in a history, especially with colicky abdominal pain and constipation, obscure neurologic changes, or photosensitivity of the skin. While the disease is generally considered to be rare in this country, Waldenström's2family studies in Sweden indicate that it occurs not infrequently in that country, or at least to such an extent that individuals manifesting undue "nervousness" or hysterical behavior...Bibliography1. Watson CJ a. in Cecil, R. L.: A textbook of medicine, ed. 7, 1947, W. B. Saunders & Co., Philadelphia, pp. 734-738. b. Watson, C. J.: Porphyria, South. M. J. 36: 359-363, 1943. c. Watson, C. J., and Larson, E. A.: Urinary coproporphyrins in health and disease, Physiol. Rev. 27: 478-510, 1947. d. Watson, C. J., and Schwartz, S.: A simple test for urinary porphobilinogen, Proc. Soc. Exper. Biol. and Med. 27: 393, 1941. e. Watson, C. J.: An enlarging concept of the porphyrins in relation to clinical medicine, Proc. Inst. Med. Chicago 16: 454-456, 1947. f. Watson, C. J.: Personal communication. Google Scholar2. Waldenström J: Studien über Porphyrie, Acta med. Scandinav. supp. 82: 1-254, 1937. 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Naval Hospital, Great Lakes, Illinois, and the Departments of Preventive Medicine and of Medicine, Western Reserve University, the School of Medicine, Cleveland, Ohio.Opinions expressed herein are those of the authors and do not necessarily represent the view of the Bureau of Medicine and Surgery, Navy Department.†Fellow, Departments of Preventive Medicine and of Medicine, Western Reserve University, the School of Medicine, Cleveland, Ohio.‡Fellow, Department of Medicine, Western Reserve University, the School of Medicine, Cleveland, Ohio. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics Cited byJuvenile Acute Intermittent Porphyria With Hypercholesterolemia and Epilepsy: A Case Report and Review of the LiteratureVariegate PorphyriaPERTTl MUSTAJOKI, M.D.Porphyria variegataPediatric aspects of the porphyriasAblagerungskrankheiten körpereigener StoffwechselprodukteNERVOUS DEGENERATION IN MALIGNANT DISEASEMedical genetics in pediatrics 1 March 1951Volume 34, Issue 3Page: 767-777KeywordsConstipationExcretionHospital medicineMedical servicesPorphyriaPorphyrinsPreventive medicineSkin diseasesSurgeryUrine ePublished: 1 December 2008 Issue Published: 1 March 1951 PDF downloadLoading ...