Key result
Reactive hyperemia-peripheral artery tonometry non-invasively and reproducibly detects early endothelial dysfunction in children.
Why the study?
Non-invasive detection of endothelial dysfunction using reactive hyperemia-peripheral artery tonometry can identify patients at risk before clinical manifestations develop.
Does reactive hyperemia-peripheral artery tonometry detect endothelial dysfunction in children and adolescents with endocrine diseases?
Does reactive hyperemia-peripheral artery tonometry detect endothelial dysfunction in children and adolescents with endocrine diseases?
Reactive hyperemia-peripheral artery tonometry (EndoPat 2000) represents a non-invasive, reproducible tool for early detection of endothelial dysfunction in pediatric endocrinopathies.
Supports non-invasive endothelial assessment in pediatric endocrinopathies; leaves open prospective validation before clinical adoption.
, cancer survivors), or immunosuppressive treatment for solid organ transplantation has been observed. Assessment of ED by means of non-invasive techniques is the gold standard for early ED detection before clinical manifestation. It is aimed to recognize patients at risk and to avoid the development and progression of more serious illnesses. Reactive hyperemia-peripheral artery tonometry is a noninvasive technique to assess peripheral endothelial function by measuring modifications in digital pulse volume during reactive hyperemia, and represents a non-invasive, reproducible and operator-independent tool able to detect precocious ED. This narrative review aimed to provide an overview of the most important papers regarding ED detection by EndoPat 2000 in children and adolescents with different endocrine diseases. A comprehensive search of English language articles was performed in the MEDLINE database without using other search filters except the publication interval between 2005 and 2020.
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Valle et al. (2021) conducted a review in Pediatric endocrinopathies. Reactive hyperemia-peripheral artery tonometry (EndoPat 2000) was evaluated on Endothelial dysfunction detection. Reactive hyperemia-peripheral artery tonometry (EndoPat 2000) represents a non-invasive, reproducible, and operator-independent tool able to detect precocious endothelial dysfunction in children.
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