Key result
Post-ECT prolactin increase correlates with higher peak heart rate and longer EEG and motor seizures.
Why the study?
Physiological parameters predicting electroconvulsive therapy effectiveness may reflect seizure propagation, prompting examination of the correlation between post-ECT prolactin and cortisol increases with clinical seizure evaluation parameters like peak heart rate.
Do physiological seizure parameters like peak heart rate correlate with hormonal changes (prolactin, cortisol) during electroconvulsive therapy?
Observational (n=131)
Do physiological seizure parameters like peak heart rate correlate with hormonal changes (prolactin, cortisol) during electroconvulsive therapy?
Peak heart rate during ECT correlates with prolactin release, suggesting tachycardia reflects seizure propagation to the diencephalon and supporting cardiovascular monitoring during ECT.
No takes yet. Share an insight, caveat, or question.
Peak heart rate may reflect seizure intensity via prolactin in ECT; hypothesis-generating and should not yet change monitoring practice.
Thörnblom et al. (2022) conducted an observational in Patients undergoing electroconvulsive therapy (n=131). Electroconvulsive therapy was evaluated on Correlation between prolactin increase after ECT and clinical seizure evaluation parameters (peak heart rate, EEG seizure duration, and motor seizure duration). In patients undergoing electroconvulsive therapy, serum prolactin increase correlated positively with peak heart rate, EEG seizure duration, and motor seizure duration.
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