Zero-contrast pre-TAVI imaging is linked to 100% procedural success and stable renal function.
Why the study?
Pre-TAVI evaluation typically uses iodinated contrast agents that may cause contrast-induced nephropathy, creating a need for a zero-contrast imaging protocol in candidates with advanced renal impairment.
Does a zero-contrast multi-modality imaging protocol allow safe and successful TAVI planning without worsening renal function in patients with symptomatic aortic stenosis and renal dysfunction?
Comparison
Multi-modality zero-contrast pre-TAVI imaging protocol
Design
Pilot survey
Follow-up
Index hospitalization
Key result
A zero-contrast imaging protocol for pre-TAVI evaluation in patients with renal dysfunction resulted in 100% procedural success and stable creatinine clearance (p=0.3).
Authors
Discussion
Loading...
Member takes
Overview
May support zero-contrast TAVI planning in renal impairment; leaves open need for prospective validation before clinical adoption.
Study Design
Type
Observational (n=10)
Structured PICO
Does a zero-contrast multi-modality imaging protocol allow safe and successful TAVI planning without worsening renal function in patients with symptomatic aortic stenosis and renal dysfunction?
P
Population
10 patients with symptomatic aortic stenosis and renal dysfunction evaluated with a zero-contrast imaging protocol prior to TAVI.
E
Exposure
Zero-contrast multi-modality imaging protocol (gadolinium-free magnetic resonance imaging, iodinated-free multislice computed tomography, lower limb arterial duplex scan ultrasound, and transesophageal echocardiography) for pre-TAVI evaluation
O
Outcome
Procedural success, procedural complications (residual aortic regurgitation, prosthesis embolization, annulus rupture, major vascular complications, stroke, or death), and stability of creatinine clearance during index hospitalizationsafety
Main Result
p-value: p=0.3
A zero-contrast multi-modality imaging protocol is feasible for pre-TAVI evaluation in patients with severe renal dysfunction, allowing successful intervention without worsening renal function.
Cite This Study
Prado et al. (2023) conducted an observational in Symptomatic aortic stenosis and renal dysfunction (n=10). Zero-contrast multi-modality imaging protocol was evaluated on Procedural success and stability of creatinine clearance (p=0.3). A zero-contrast imaging protocol for pre-TAVI evaluation in patients with renal dysfunction resulted in 100% procedural success and stable creatinine clearance (p=0.3).