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February 26, 2019Cardiovascular MedicineOpen Access

Minimal use of contrast media in patients with severe chronic kidney disease undergoing transcatheter aortic valve implantation

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Why the study?

Patients with severe kidney disease and severe aortic stenosis requiring TAVI represent a growing cohort, prompting evaluation of approaches to minimize contrast media use.

Does a novel integrated approach including gadolinium-free MR improve safety by minimizing contrast media use in patients with severe kidney disease and severe aortic stenosis requiring TAVI?

Population

Patients with severe kidney disease and severe aortic stenosis requiring TAVI

Comparison

Novel integrated approach including gadolinium-free MR to minimize contrast media use

Authors

MBMiriam BrinkertBBBart De BoeckJPJoanna Petryka

Discussion

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Member takes

Overview

Gadolinium-free MR may enable contrast minimization during TAVI in severe CKD; leaves open whether this improves safety or outcomes.

Structured PICO

Does a novel integrated approach including gadolinium-free MR improve safety by minimizing contrast media use in patients with severe kidney disease and severe aortic stenosis requiring TAVI?

P
Population
Patients with severe kidney disease and severe aortic stenosis requiring transcatheter aortic valve implantation (TAVI)
I
Intervention
Novel integrated approach, including gadolinium-free magnetic resonance tomography (MR) to minimize use of contrast media
O
Outcome
Feasibility and safetysafety

A novel integrated approach using gadolinium-free MR is being investigated to minimize contrast media use in high-risk TAVI patients with severe kidney disease.

Cite This Study

Brinkert et al. (2019) studied this question.

synapsesocial.com/papers/6a719723f44fa9f079df5c72https://doi.org/10.4414/cvm.2019.02021
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Zero-contrast imaging for the assessment of transcatheter aortic valve implantation in candidates with renal dysfunction2023 · 2 citations
  2. 2Transcatheter aortic‐valve implantation with one single minimal contrast media injection2014 · 14 citations
  3. 3Contrast-free (Zero-contrast) TAVR for Severe Aortic Stenosis in Patient with Chronic Kidney Disease2018 · 4 citations
  4. 4A Contrast Frugal Approach to Transcatheter Aortic Valve Replacement in Chronic Kidney Disease: A Pilot Study2022 · 1 citations
  5. 5A Novel Protocol for Contrast-Free Transcatheter Aortic Valve Replacement Evaluation and Implantation2024 · 2 citations