What question did this study set out to answer?

To evaluate the safety and diagnostic efficacy of TRUE Test panels 1.1, 2.1, and 3.1 in pediatric and adolescent patients with suspected allergic contact dermatitis.

August 1, 2011Dermatitis

Safety and Efficacy Evaluation of TRUE TEST Panels 1.1, 2.1, and 3.1 in Children and Adolescents

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To evaluate the safety and diagnostic efficacy of TRUE Test panels 1.1, 2.1, and 3.1 in pediatric and adolescent patients with suspected allergic contact dermatitis.
Enrolled 102 consecutive patients aged 6 to 18 years referred for suspected allergic contact dermatitis between December 2008 and October 2009 in an open-label prospective study.
Applied standardized patch tests containing 28 allergens for 48 hours, evaluating cutaneous reactions on days 3 and 7, with a safety follow-up at 3 weeks.
Overall, 76.2% of evaluated subjects (77/101) showed at least one positive allergic reaction to the 28 tested substances.
The most common contact allergens were nickel sulfate (29.7%), p-tert-butylphenol formaldehyde resin (16.8%), wool alcohols (15.8%), fragrance mix (12.9%), and cobalt dichloride (12.9%).
No significant differences occurred in adverse event severity, patch removal stinging or burning, or persistent reactions across age, sex, or racial cohorts.

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Implication

Prospective study demonstrates the safety and diagnostic efficacy of epicutaneous patch testing in children and adolescents, indicating its clinical utility for pediatric allergic contact dermatitis.

Cite This Study

Jacob et al. (2011) studied this question.

synapsesocial.com/papers/6aa2d7e415b648e24213a1f9 https://doi.org/10.2310/6620.2011.11011

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Implication

Prospective study demonstrates the safety and diagnostic efficacy of epicutaneous patch testing in children and adolescents, indicating its clinical utility for pediatric allergic contact dermatitis.

Safety and Efficacy Evaluation of TRUE TEST Panels 1.1, 2.1, and 3.1 in Children and Adolescents

Key Points

Discussion

Implication

Cite This Study

Safety and Efficacy Evaluation of TRUE TEST Panels 1.1, 2.1, and 3.1 in Children and Adolescents

Key Points

Discussion

Implication

Cite This Study

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