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It included many of the same allergens present in other screening series, with allergens arranged in panels of decreasing yield. Given that frequencies of contact allergy and exposures vary with time, the ACDS Core Allergen Series was updated in 2013, 2017, and again in 2020, at which point it was expanded to include 90 allergens. The ACDS used a Delphi technique to reach agreement for updates in the 2027 ACDS Core Allergen Series. In the 2027 Series, the following changes were made: the first 4 panels correlate with recommended pediatric core allergens; aqueous and volatile allergens are grouped in panels II, III and VI to emphasize that they should be prepared immediately prior to patch test placement; 7 allergens were replaced; the concentration of nickel sulfate was increased to 5%, and the concentration of propylene glycol was increased to 100%.
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Dunnick et al. (2026) studied this question.
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