Key result
This editorial discusses the Hygia Chronotherapy Trial, which investigated whether evening administration of antihypertensive drugs improves cardiovascular risk reduction compared to morning dosing.
Why the study?
Does evening administration of antihypertensive drugs improve cardiovascular risk reduction in patients with high blood pressure?
Does evening administration of antihypertensive drugs improve cardiovascular risk reduction in patients with high blood pressure?
This editorial discusses the surprising results of the Hygia Chronotherapy Trial regarding the timing of antihypertensive medication administration.
On October 22, 2019 the European Heart Journal published a large randomized trial by Spanish investigators led by Ramon C. Hermida entitled "Bedtime hypertension treatment improves cardiovascular risk reduction: the Hygia Chronotherapy Trial" (European Heart Journal (2019)0, 1–12; doi:10.1093/eurheartj/ehz754). The question on when and how to apply antihypertensive drugs to patients with high blood pressure is a highly interesting scientific and clinically relevant question and has been a matter of debate for many years. In this trial the investigators randomized patients either to morning application of their antihypertensive drugs or administered antihyperten-sives in the evening. For their study, they enrolled an impressive number of over...
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Thomas F. Lüscher (2020) conducted an editorial in High blood pressure. Evening administration of antihypertensive drugs vs. Morning administration of antihypertensive drugs was evaluated. This editorial discusses the Hygia Chronotherapy Trial, which investigated whether evening administration of antihypertensive drugs improves cardiovascular risk reduction compared to morning dosing.
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