Key result
ANP gene G664A polymorphism shows no association with ischemic stroke risk.
Why the study?
Is the ANP gene G664A polymorphism associated with an increased risk of ischemic cerebrovascular disease?
Population
731 individuals, comprising 436 patients with ischemic cerebrovascular disease and 295 community control…
Comparison
Presence of atrial natriuretic peptide gene… vs Absence of the polymorphism / community control…
Design
Case-control
Authors
Loading...
No association with ischemic stroke risk; leaves open other ANP variants or pathways in cerebrovascular disease.
Case-Control (n=731)
Is the ANP gene G664A polymorphism associated with an increased risk of ischemic cerebrovascular disease?
The ANP gene G664A polymorphism does not appear to be a significant genetic risk factor for ischemic stroke.
Hassan et al. (2001) conducted a case-control in Ischemic cerebrovascular disease (n=731). ANP gene G664A polymorphism vs. Community control subjects was evaluated on Frequency of the G664A variant. The ANP gene G664A polymorphism had a similar frequency in patients with ischemic cerebrovascular disease and community controls, indicating it is unlikely to be a major risk factor for ischemic stroke.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: