Key result
En bloc resection achieves curative outcome for giant retroperitoneal liposarcoma with no 1-year recurrence.
Why the study?
Retroperitoneal liposarcomas can grow to astronomical proportions before manifesting noticeable symptoms, making prompt diagnosis dilatory and surgical resection challenging.
Case Report (n=1)
En bloc resection is an appropriate and curative treatment modality for giant retroperitoneal liposarcoma.
Supports en bloc resection in select giant retroperitoneal liposarcoma cases; hypothesis-generating and requires validation in larger cohorts.
Liposarcomas are exceedingly rare entities that evoke malignant transformation of connective tissue and fat cells. These tumours occur throughout the soft tissues of the body, afflicting a myriad of regions. In the adult population, liposarcomas represent the most prevalent subtype of sarcomas, and often arise de novo. Retroperitoneal liposarcomas (RLS) are a ubiquitous subset of sarcomas that, due to their deep location in the hollow abdomen, can grow to astronomical proportions before manifesting any noticeable symptoms; a prompt diagnosis of RLS is therefore often rendered dilatory. We hereby delineate the case of a 43-year-old woman who presented with vague left hemiabdominal distention and discomfort. A subsequent computed tomography scan divulged a giant retroperitoneal growth impaling on and thus displacing the pancreas. A compartmental, en bloc resection was performed, with subsequent histopathology of the excised specimen revealing a well-differentiated liposarcoma. The surgical intervention was curative and led to an uneventful recovery. This paper highlights the pertinence of surgical management as an appropriate treatment modality for a complete resection of RLS.
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Almas et al. (2020) conducted a case report in Giant Retroperitoneal Liposarcoma (n=1). En bloc compartmental resection was evaluated on Surgical outcome and recurrence. En bloc resection of a giant retroperitoneal liposarcoma encasing adjacent organs was curative, resulting in an uneventful recovery with no recurrence at one-year follow-up.
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