Key result
Noninvasive positive-pressure ventilation significantly reduced systolic blood pressure from 147 to 138 mm Hg and heart rate from 85 to 75 bpm in patients with acute exacerbations of COPD.
Why the study?
Does noninvasive positive-pressure ventilation improve systemic blood pressure and heart rate variability in patients with acute exacerbations of COPD?
Population
23 patients with acute exacerbations of chronic obstructive pulmonary disease (COPD)
Design
Cohort
Follow-up
Acute (during and immediately after NPPV withdrawal)
Authors
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Supports acute parasympathetic benefits of NIV in COPD exacerbations; leaves open effects on HR variability and clinical outcomes.
Cross-Sectional (n=23)
No
Does noninvasive positive-pressure ventilation improve systemic blood pressure and heart rate variability in patients with acute exacerbations of COPD?
Absolute Event Rate: 138% vs 147%
p-value: p=<0.001
Noninvasive positive-pressure ventilation acutely improves parasympathetic neural control of heart rate and reduces blood pressure in patients with COPD exacerbations.
Skyba et al. (2007) conducted a cross-sectional in Acute exacerbations of chronic obstructive pulmonary disease (COPD) (n=23). Noninvasive positive-pressure ventilation (NPPV) vs. Pre-NPPV baseline was evaluated on Systolic blood pressure (p=<0.001). Noninvasive positive-pressure ventilation significantly reduced systolic blood pressure from 147 to 138 mm Hg and heart rate from 85 to 75 bpm in patients with acute exacerbations of COPD.
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