Key result
Non-Newtonian modeling alters wall shear stress only in high-velocity regions, matching Newtonian predictions on aneurysms.
In computational modeling of carotid aneurysms, Newtonian and non-Newtonian blood models yield similar wall shear stress predictions on the aneurysmal wall, though differences exist in high velocity gradient arterial regions.
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May justify Newtonian assumptions for aneurysmal wall shear stress in carotid models; leaves open non-Newtonian effects in high-gradient arterial regions.
Flow dynamics plays an important role in the pathogenesis and treatment of cerebral aneurysms. The temporal and spatial variations of wall shear stress in the aneurysm are hypothesized to be correlated with its growth and rupture. In addition, the assessment of the velocity field in the aneurysm dome and neck is important for the correct placement of endovascular coils. This work describes the flow dynamics in a patient‐specific model of carotid artery with a saccular aneurysm under Newtonian and non‐Newtonian fluid assumptions. The model was obtained from three‐dimensional rotational angiography image data and blood flow dynamics was studied under physiologically representative waveform of inflow. The three‐dimensional continuity and momentum equations for incompressible and unsteady laminar flow were solved with a commercial software using non‐structured fine grid with 283 115 tetrahedral elements. The intra‐aneurysmal flow shows complex vortex structure that change during one pulsatile cycle. The effect of the non‐Newtonian properties of blood on the wall shear stress was important only in the arterial regions with high velocity gradients, on the aneurysmal wall the predictions with the Newtonian and non‐Newtonian blood models were similar.
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Valencia et al. (2005) studied Saccular aneurysm of the right internal carotid artery (n=1). Non-Newtonian fluid assumption vs. Newtonian fluid assumption was evaluated on Wall shear stress and flow dynamics. Non-Newtonian blood properties affected wall shear stress only in arterial regions with high velocity gradients, while predictions on the aneurysmal wall were similar to Newtonian models.
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