Key result
Basilar artery aneurysm simulations show asymmetric outflow increases wall shear stress amid complex vortex structures.
Computational fluid dynamics modeling demonstrates that asymmetric outflow increases wall shear stress in basilar artery terminal aneurysms, which may have implications for understanding aneurysm growth and rupture.
May refine basilar aneurysm hemodynamics understanding; leaves open clinical relevance for rupture risk.
Blood flow dynamics play an important role in the pathogenesis and treatment of intracranial aneurysms. The evaluation of the velocity field in the aneurysm dome and neck is important for the correct placement of endovascular coils, in addition the temporal and spatial variations of wall shear stress in the aneurysm are correlated with its growth and rupture. The present numerical investigation describes the hemodynamics in two models of terminal aneurysm of the basilar artery. Aneurysm models with an aspect ratio of 1.0 and 1.67 were studied. Each model was subject to a steady, sinusoidal and physiologically representative waveform of inflow for a mean Reynolds number of 560. Symmetric and asymmetric outflow conditions in the branches were also studied. The three-dimensional continuity and the Navier-Stokes equations for incompressible, unsteady laminar flow with Newtonian properties were solved with a commercial software using non structured grids with 61334 and 65961 cells for models 1 and 2, respectively. The grids were primarily composed of tetrahedral elements. The intra-aneurysmal flow was unsteady for all input conditions and in both models, the flow always showed a complex vortex structure. The inflow and outflow zones in the aneurysm neck were determined. The wall shear stress on the aneurysm showed large temporal and spatial variations. The asymmetric outflow increased the wall shear stress in both models.
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Álvaro Valencia (2005) studied Terminal aneurysm of the basilar artery. Asymmetric outflow conditions vs. Symmetric outflow conditions was evaluated on Wall shear stress and intra-aneurysmal flow dynamics. Numerical simulation of terminal basilar artery aneurysms showed unsteady intra-aneurysmal flow with complex vortex structures, and asymmetric outflow increased wall shear stress in both models.
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