Key result
Aneurysm geometry significantly alters wall shear stress and hemodynamics in computational fluid dynamics simulations.
Why the study?
A better understanding of the mechanisms underlying aneurysm pathophysiology is crucial for developing new preventive procedures and therapeutic strategies.
Computational fluid dynamics simulations demonstrate that aneurysm geometry and shape directly influence wall shear stress and blood velocity patterns, highlighting factors potentially related to rupture risk.
Hypothesis-generating for geometry-driven rupture risk; leaves open validation in patient-specific clinical models.
Nowadays, the cerebral aneurysm is an abnormal focal dilation of a brain artery which is considered as a serious and potentially life-threatening condition. The rupture of an aneurysm causes subarachnoid hemorrhage (SAH) and is associated with high rates of morbidity and mortality. A better understanding of the mechanisms underlying aneurysm pathophysiology is crucial for the development of new preventive procedures and therapeutic strategies. This study focuses on the modeling and simulation of the blood flow analysis using simplified aneurysm models to perform early prediction on the geometrical effects of hemodynamics. The investigation involves three simplified models of aneurysms reconstructed using Solidworks 2019 , in which the aneurysms are developed at the bifurcation. The qualitative comparison of the hemodynamics between three models was obtained and the geometrical effects were evaluated. The results show that the differences in shape and geometry on aneurysms affect the hemodynamics trend and are capable to apply for further understanding of problems regarding hemodynamics in the patient.
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Hong et al. (2020) studied Cerebral aneurysm. Different geometrical shapes of aneurysm models was evaluated on Wall shear stress and velocity distribution. Differences in the shape and geometry of simplified cerebral aneurysm models significantly affected wall shear stress and hemodynamic trends in computational simulations.
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