A Prospective, Comparative Study of Effect of Bupivacaine-Fentanyl and Bupivacaine-Tramadol in Patient Undergoing Lower Abdominal Surgery in Spinal Anaesthesia

BACKGROUND local anaesthetic agents are used with good pharmacokinetic profile. Bupivacaine is a potent amide local anaesthetic prolonged anaesthesia along with that it produces more sensory than motor block. Only limitation with the use of is its cardio toxicity in high dose, it has been found that a mixture of local anaesthetic and opioids has supra additive in the spinal cord posterior horn pain transmission. The requirement of local anaesthetic will be submaximal, which and maintains the overall analgesic effect over the time, and with fewer side effects. AND METHODS is a prospective study conducted in the department of anaesthesia and critical care at Konaseema institute of medical science, , Andhra Pradesh. This study was conducted between 2012-2013 and during this period 140 patients were included to this study as per the exclusion and inclusion criteria. onset of sensory block time to reach T10 level was 4.22 and 4.2 min respectively in group BF and group BT, which statistically significant with P value <0.05. Peak sensory level achieved in group BF was T4 but in group BT it was T5. Time to reach peak sensory level was 10.6 min in group BF and 10.8 in group BT which is statistically significant. Onset of block in group BF was 3.6 min and in group BT it was 4.2 mins. Total duration of motor block was more in BF group that 280.4 min than group BT that is 260.4 min. Mean duration of 1 of rescue analgesia was 432.66 min in group BF and 400.20 min in group BT. our study we have found that there is no difference between the mean change in blood pressure, heart rate and respiratory , between two groups, which is supported by the study of various authors. Time to reach peak T10 level was 4.22 min and 4.39 min in group BF and BT respectively which is similar to the work of other authors and peak sensory level achieved by BF higher than BT that is T4. Mean duration of sensory block was little higher in Group BT than the group BF which is similar the work of Ravishankar et al., A. M. kaki et al.